TikTok Benadryl Challenge poses significant overdose health risks.

Medical Mythbusting Commentary for September 1, 2020

Benadryl Makers Beg Parents to Beware TikTok Challenge After Oklahoma Teen Reportedly Dies of Overdose

Consequences of overdose:

Flushing due to cutaneous vasodilation (“red as a beet”)
Anhydrosis (“dry as a bone”)
Hyperthermia due to loss of sweating (“hot as a hare”)
Blurry vision due to nonreactive mydriasis and paralysis of accommodation (“blind as a bat”)
Agitated delirium (“mad as a hatter”)
Urinary retention (“full as a flask”)
Decreased bowel sounds