The variant is to model outcome predictions as Asimov’s Foundation series’ Mule was in Hari Seldon’s Psychohistory projections. Extracting six doses per vial instead of five is like Jean Luc Picard being told there are five lights when there are four.

Medical Mythbusting Commentary for January 29, 2021

John Ivison: Prepare for dose of reality — vaccines don’t guarantee a quick return to normal

Is it five doses or six? It’s both. The Pfizer dispute, explained