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Category: Molecular Medicine

There are many branches of stroke research from prevention, emergency treatment, to rehabilitation technologies and therapies. When a person suffers a stroke, it is a race to try to minimize the death of brain cells that follow the initial damage and oxygen deprivation.

Original broadcast date: May 31, 2009 How well can cancer specialists, oncologists, assess how well a particular treatment is destroying a tumour? It is true that there are methods to make this determination but it could take weeks of observation before knowing whether the tumour has shrunk. Is it possible to develop a means of [...]

Original broadcast date: May 31, 2009 How well can cancer specialists, oncologists, assess how well a particular treatment is destroying a tumour? It is true that there are methods to make this determination but it could take weeks of observation before knowing whether the tumour has shrunk. Is it possible to develop a means of [...]

Original broadcast date: March 22, 2009 Are you getting what you ordered when dining in a restaurant that serves seafood? This is important on many levels, from honest business practices to endangered or protected species preservation to managing allergy risks. How can inspectors, and by extension the public, learn about the true source of their [...]

Original broadcast date: March 8, 2009 How do you know that the disinfectant that claims to kill over 99 per cent of bacteria actually does just that? What are the mechanisms of action that result in this effect? Today, we are going to learn about biofilms, what they are, what they do, how we are [...]

Original broadcast date: January 11, 2009 Recent reports from the Canadian Alzheimer’s Society state that the number of Canadians who will develop Alzheimer Disease will double in 25 years to 1.3 million people. They are urging more funding for research to find a means to treat and perhaps prevent the changes that occur within the [...]

Original broadcast date: January 6, 2008 When we last spoke to Dr. Ulli Krull, he talked about the development of a device that could be used to detect chemical substances in a given environment. For lack of a better analogy, it was like a Star Trek Tricorder. His present projects include developing biosensors that are [...]

Despite exposure to many cancer-causing agents or carcinogens in our environment, the human body has a way to repair damaged DNA that can prevent the development of tumours. A new study published November 11, 2008 in the online edition of Proceedings of the National Academy of Sciences of the USA (PNAS), scientists have identified a [...]

Scientists say they are gaining insight into how the brain rewires itself as it learns new things, potentially helping them move toward better treatments for mental illness and brain injuries. Researchers report in a new study, published in the August 8, 2008 issue of Cell, that a protein appears to tell the brain that it’s [...]

Researchers from University College London have gained a new understanding of how changes in the immune system can foreshadow the expression of Huntington’s disease by 16 years. The research on this fatal neurodegenerative disease was published online in the Journal of Experimental Medicine and shed some light on possible therapies that would target the immune [...]

Physicians use various imaging technologies to screen, diagnose and follow cancerous tumours. The information they provide will show the gross location and extent of the tumour. However, cancer surgeons today operate “blind” with no clear way of determining in real-time whether they have removed all of the diseased tissue, which is the key to successful [...]

Undercooked chicken, eggs sandwiches that have gone bad, contaminated water sources while on vacation and just plain poor sanitation and agricultural practices, all the factors and more can lead to salmonella transmission and infection. What has begged the question for some time is why this particular bacterium can cause so fierce an infection while the [...]

We hear the commercials on radio and TV asking people to donate blood. It is sometimes followed by a brief notice or announcement that they are looking for blood of a particular type. This ongoing public canvassing for blood donations illustrates the issue of blood product shortages. There is always a need for blood products [...]

Eye diseases such as retinitis pigmentosa and macular degeneration result in the loss of vision in a slow and unrelenting fashion due to the deteriorating and damaged retina. A team of scientists at the Schepens Eye Research Institute and Harvard Medical School has published a study in the March issue of Investigative Ophthalmology and Visual [...]

Research into breast cancer treatments continues apace and a new study to be presented at the end of May at the American Society of Clinical Oncology annual meeting in Chicago introduces us to a new treatment that blocks signals within the cancer cell that cause it to grow and spread. Dr. Kathy Pritchard, Senior scientist [...]

Food science is a major topic for discussion on Sunday House Call. To me, there was one seminal interview that beautifully encapsulated the exciting science and discovery of the biochemistry of foods and the role they play in fighting cancer.


The interview in June 2006 featured Dr. Richard Beliveau, author of Foods That Fight Cancer: Preventing Cancer through Diet. To date, 200,000 copies of the book have sold in Canada, an incredible number given that 5,000 is considered a best-seller.


As we discussed in our last interview of June 25, 2006, phytochemicals in the foods we eat can play a significant role in cancer prevention and overall health; literally a non-toxic version of chemotherapy. Our current Western diets seem to have weakened our body’s ability to fend off certain types of cancer among other diseases. In short, our society’s food choices have become divorced from reality and from our biology and physiology.


It seems the next logical step was to expand on the science and, at the same time, produce a book on how to incorporate these foods into our diet. With that in mind sprung his next book, Cooking with Foods that Fight Cancer.


  • Dr. Richard Beliveau, author of Foods That Fight Cancer: Preventing Cancer Through Diet and Cooking with Foods that Fight Cancer, Biochemistry professor and Chair in the Prevention and Treatment of Cancer at the University of Quebec at Montreal and director of the Molecular Medicine Laboratory at Sainte Justine Hospital. He is also professor of Surgery at the Faculty of Medicine at the University of Montreal.

Several months ago we talked with Dr. Paul Ridker about his study of heart disease risk markers in women that contributed to the development of the Reynolds Risk Score using C-reactive protein as a marker or indicator of the ten-year risk of developing a heart attack. Research into the prevention of cardiovascular disease continues apace. [...]

Cancer treatment success depends on early diagnosis. Lung cancer, unfortunately for many, is discovered too late. Various imaging technologies have been used to try to detect early lung cancer with some success and new detection methods are under development. In a recent study, US scientists have developed a genetic test, the results of which are [...]

What is pharmacogenomics? What research is taking place in pharmacogenomics right now? What role will it play in patient care as we try to live longer, even following cancer, diabetes, heart & stroke? Pharmacogenomics is an emerging science that integrates the patient’s genomic data so as to personalize treatment and thereby improve the effectiveness and [...]

As we reported on Sunday House Call in August Scientists from the Salk Institute for Biological Studies and the Scripps Research Institute reported progress in understanding how aging contributes to the development of Alzheimer Disease. There are many avenues of study and exploration to try to understand the mechanisms behind the expression of the disease. [...]

We have seen numerous studies in basic science research produce results that surprise the investigator and open up new insights into the pathophysiology or mechanism of disease. A study published in the July 13, 2006 online issue of the Journal of Clinical Investigation found that a protein previously linked to the development of type 2 [...]

Chronic stress seems to trigger the premature aging of immune system cells, a new study suggests. Although people who are under stress for long periods often look haggard, scientists don’t understand how chronic stress causes damage at the cellular level. The new research focused on one sign of biological aging – caps of DNA and [...]

Genetic research continues to broaden our understanding of the mechanism or pathophysiology of diseases. Reports seem to present themselves daily about new avenues for treatments of once incurable or uncontrollable illnesses. A team from the Scripps Research Institute and the University of California School of Medicine has developed compounds that reactivate the gene responsible for [...]

Researchers at Manchester’s Faculty of Life Sciences, in conjunction with St George’s, University of London, are developing drugs designed to stop allergens from entering the body, which will render them harmless and stop the suffering. The head of the research team is Professor David Garrod and he says the research takes a completely new approach [...]