Madely Health Headlines Commentary for May 14, 2013

Angelina Jolie has double mastectomy to prevent BRCA-induced breast cancer Play Now | Play in Popup | Download

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Angelina Jolie has double mastectomy due to breast cancer risk

Madely Health Headlines Commentary for May 7, 2013

FDA wants tanning beds risks to be regulated like CT scanners Play Now | Play in Popup | Download

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FDA proposes tougher regulations on tanning beds

Madely Health Headlines Commentary for May 2, 2013

Study shows how cancer cells recruit other cell type to aid in its spread Play Now | Play in Popup | Download

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Scientists Decode “Molecular Chatter” That Makes Cancer Cells Spread

Reference:

“Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis”; Younghun Jung, Jin Koo Kim, Yusuke Shiozawa, Jingcheng Wang, Anjali Mishra, and others; Nature Communications 4, Article number 1795, published online 30 April 2013; DOI:10.1038/ncomms2766; Link to Abstract.

Madely Health Headlines Commentary for April 25, 2013

Focused-beam-ultrasound trial will investigate efficacy to treat early stage prostate cancer Play Now | Play in Popup | Download

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Clinical trial first for less invasive procedure to treat prostate cancer

Madely Health Headlines Commentary for March 7, 2013

Breath test for stomach cancer show promise as it moves into larger population clinical trials Play Now | Play in Popup | Download

Madely Health Headlines Commentary for February 28, 2013

Study suggests that rate of breast cancer in young women has increased by 13 per million young women in 30 years Play Now | Play in Popup | Download

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Study Sees More Breast Cancer at Young Age

Reference:

Incidence of Breast Cancer With Distant Involvement Among Women in the United States, 1976 to 2009

Madely Health Headlines Commentary for February 13, 2013

Not all kidney cancer requires immediate surgical intervention Play Now | Play in Popup | Download

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‘Watch and Wait’ Approach Often Best for Older Patients With Kidney Cancer

Reference:

The findings are to be presented at an  American Society of Clinical Oncology conference in New York City on February 16, 2013. Research presented at medical meetings is typically considered preliminary until published in a peer-reviewed journal.

Madely Health Headlines Commentary for January 23, 2013

Attacking B-cell lymphoma without chemotherapy using gold nanoparticle Play Now | Play in Popup | Download

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New way to kill lymphoma without chemotherapy: Golden nanoparticle starves cancer cell to death

Reference:

S. Yang, M. G. Damiano, H. Zhang, S. Tripathy, A. J. Luthi, J. S. Rink, A. V. Ugolkov, A. T. K. Singh, S. S. Dave, L. I. Gordon, C. S. Thaxton. Biomimetic, synthetic HDL nanostructures for lymphoma. Proceedings of the National Academy of Sciences, 2013; DOI:10.1073/pnas.1213657110

Madely Health Headlines Commentary for December 24, 2012

Virus used in mouse model study to destroy prostate cancer tumours Play Now | Play in Popup | Download

Madely Health Headlines Commentary for November 22, 2012

The effects of overdiagnosis of breast cancer using screening mammography Play Now | Play in Popup | Download

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Cancer Survivor or Victim of Overdiagnosis?

Reference:

Effect of Three Decades of Screening Mammography on Breast-Cancer Incidence

Madely Health Headlines Commentary for November 19, 2012

Multivitamins do little to reduce cancer risk in male physicians over 50:study Play Now | Play in Popup | Download

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Study: Multivitamins may slightly lower cancer risk in men but not their odds of heart disease

Reference:

Multivitamins in the Prevention of Cancer in Men: The Physicians’ Health Study II Randomized Controlled Trial

Madely Health Headlines Commentary for November 9, 2012

The rationale of why testicular cancer screening using a pregnancy test is not recommended Play Now | Play in Popup | Download

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Reddit comic about Canadian man’s positive pregnancy test sparks cancer diagnosis

Madely Health Headlines Commentary for November 8, 2012

New cancer biomarker protein may lead to development of early detection and treatment Play Now | Play in Popup | Download

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One test may ‘find many cancers’

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The DSB Biomarkers Pilot Study

Madely Health Headlines Commentary for November 1, 2012

Common food preservative may help treat head and neck cancers but human clinical trails needed to confirm results Play Now | Play in Popup | Download

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Tumor Growth May Be Slowed Or Halted By Common Food Preservative

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Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1

Madely Health Headlines Commentary for October 25, 2012

Aspirin use improves colon cancer survival for those who have a specific mutation called PIK3CA Play Now | Play in Popup | Download

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Aspirin has selective benefit in colorectal cancer

Reference:

X. Liao et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. New England Journal of Medicine, Volume 367, Oct. 25, 2012, p. 1596. doi: 1056/NEJMoa1207756

Madely Health Headlines Commentary for October 10, 2012

The importance of colorectal cancer screening Play Now | Play in Popup | Download

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Max Keeping’s next battle: Former CTV anchor faces surgery for colorectal cancer

Madely Health Headlines Commentary for October 3, 2012

Targeted chemotherapy for HER2 breast cancer patients shows good results in phase 3 study Play Now | Play in Popup | Download

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Breast cancer treatment targets tumours with few side effects

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Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

Madely Health Headlines Commentary for September 24, 2012

Breast cancer study identifies distinct genetic types Play Now | Play in Popup | Download

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Breast cancer study finds four distinct genetic types

Reference:

Comprehensive molecular portraits of human breast tumours 

Madely Health Headlines Commentary for September 21, 2012

Major cancer research drive at MD Anderson Play Now | Play in Popup | Download

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Largest cancer center in US launches major initiative to cure 8 forms of the disease

Madely Health Headlines Commentary for September 18, 2012

Shingles does not increase cancer risk nor is it associated with cancer Play Now | Play in Popup | Download

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Shingles patients don’t have higher risk of cancer, study finds

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Risk of cancer among patients with herpes zoster infection: a population-based study 

Madely Health Headlines Commentary for August 30, 2012

ASA may improve survival for men with aggressive prostate cancer Play Now | Play in Popup | Download

Source:

Aspirin May Prolong Prostate Cancer Survival

Reference:

“Aspirin Use and the Risk of Prostate Cancer Mortality in Men Treated With Prostatectomy or Radiotherapy”; Kevin S. Choe, Janet E. Cowan, June M. Chan, Peter R. Carroll, Anthony V. D’Amico, and Stanley L. Liauw; Journal of Clinical Oncology, published online 27 August 2012; DOI:10.1200/JCO.2011.41.0308; Link to Abstract.
Additional source: UT Southwestern Medical Center.

Madely Health Headlines Commentary for July 25, 2012

Melanoma risk directly affected by tanning bed UV exposure Play Now | Play in Popup | Download

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Melanoma on Rise with Indoor Tanning

Reference:

Boniol M, et al “Cutaneous melanoma attributable to sunbed use: Systematic review and meta-analysis” BMJ 2012; DOI: 10.1136/bmj.e4757.

Madely Health Headlines Commentary for July 20, 2012

Prostate cancer surgery results no different from not doing the surgery: study Play Now | Play in Popup | Download

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Prostate Cancer Surgery Fails to Cut Death Rate in Study

Reference:

Radical Prostatectomy versus Observation for Localized Prostate Cancer

Madely Health Headlines Commentary for June 14, 2012

Cold virus used to attack cancer cells Play Now | Play in Popup | Download

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Cold virus holds promise as cancer therapy: study

Reference:

Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Madely Health Headlines Commentary for June 5, 2012

Early data using targeted breast cancer therapy shows promise but study remains unpublished for now Play Now | Play in Popup | Download

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Study: ‘Smart Bomb’ Drug Attacks Breast Cancer

Madely Health Headlines Commentary for May 23, 2012

Google algorithms help identify biomarker proteins for pancreatic cancer Play Now | Play in Popup | Download

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Google algorithm proves extremely useful in cancer study

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Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes

Madely Health Headlines Commentary for May 21, 2012

Cancer risk increased with sleep apnea Play Now | Play in Popup | Download

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Sleep Apnea Has Higher Risk Of Cancer Mortality

Reference:

http://www.med.wisc.edu/news-events/news/sleep-apnea-associated-with-higher-mortality-from-cancer/37687

Madely Health Headlines Commentary for May 3, 2012

HIV treatment with modified T cells successful in small study Play Now | Play in Popup | Download

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Gene Therapy Safe in Decade-Long HIV Study That May Widen Use

Reference:

Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells

Madely Health Headlines Commentary for April 27, 2012

Data does not support routine vitamins and other supplements to prevent cancer Play Now | Play in Popup | Download

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Supplements May Increase Cancer Risk

Reference:

Martinez ME, et al “Dietary supplements and cancer prevention: Balancing potential benefits against proven harms” J Natl Cancer Inst 2012; DOI: 10.1093/jnci/djs195.

Madely Health Headlines Commentary for April , 2012

Discovery of breast cancer subtypes may lead to improved treatment Play Now | Play in Popup | Download

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Study extends breast cancer subtypes to 10 from 4: Video

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

Madely Health Headlines Commentary for April 12, 2012

Human memory recall used as basis for dental x-ray brain tumour study: A lesson in how not to do a study Play Now | Play in Popup | Download

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Dental x-rays linked to common brain tumor

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Dental x-rays and risk of meningioma

Madely Health Headlines Commentary for April 10, 2012

Sunscreen use recommendations and new FDA labelling regulations Play Now | Play in Popup | Download

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The Push for Daily Sunscreen
Few People Apply It the Right Way, New Labels Try to Help; a Shot Glass of Protection in the Morning

Madely Health Headlines Commentary for April 5, 2012

Another observational study on green vegetables and legumes and cancer outcomes Play Now | Play in Popup | Download

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Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study

Reference:

Not published

Madely Health Headlines Commentary for April 3, 2012

Recognizing the impact of mammogram false positive results Play Now | Play in Popup | Download

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Study finds some early breast cancer overdiagnosed

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Overdiagnosis of Invasive Breast Cancer Due to Mammography Screening: Results From the Norwegian Screening Program

Madely Health Headlines Commentary for March 29, 2012

Increases in obesity prevalence being considered as a possible cause for increases in certain cancers Play Now | Play in Popup | Download

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Obesity-Linked Cancers Increase

Reference:

 Annual Report to the Nation on the Status of Cancer

Madely Health Headlines Commentary for March 21, 2012

ASA study for cancer prevention interesting but leaves out large studies stating the opposite and uses studies not originally designed for cancer outcomes Play Now | Play in Popup | Download

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More research touts aspirin for cancer prevention

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Aspirin Benefits May Include Cancer Prevention

Madely Health Headlines Commentary for January 25, 2012

Clinical relevance of drug to slow low grade prostate cancer unclear Play Now | Play in Popup | Download

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Drug may help slow prostate tumour growth

Reference:

The Lancet: Dutasteride in localised prostate cancer management

Madely Health Headlines Commentary for January, 2012

Study concludes ASA should not be used for primary prevention of heart disease because side effects outweigh benefits Play Now | Play in Popup | Download

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Aspirin a day may be harmful, study says

Reference:

Effect of Aspirin on Vascular and Nonvascular Outcomes

Madely Health Headlines Commentary for December 9, 2011

Anti-androgen prostate cancer therapy does not increase risk of heart-related deaths Play Now | Play in Popup | Download

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Hormone Drugs Might Not Raise Heart-Related Deaths in Prostate Patients

Reference:

Association of Androgen Deprivation Therapy With Cardiovascular Death in Patients With Prostate Cancer: A Meta-analysis of Randomized Trials

Madely Health Headlines Commentary for November 29, 2011

Hospital parking fees are user fees/Health Canada removes Avastin's indication to treat HER2 negative breast cancer Play Now | Play in Popup | Download

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Ottawa doc calls for end to rich hospital parking fees

Avastin no longer OK for metastatic breast cancer

Tonelli M, et al “Recommendations on screening for breast cancer in average-risk women aged 40-74 years” CMAJ 2011; DOI: 10.1503/cmaj.110334.

Additional source: CMAJ
Source reference:
Gøtzsche PC “Time to stop mammography screening?” CMAJ 2011; DOI: 10.1503/cmaj.111721.

Breast cancer screening for 40-49 year old women not supported by solid evidence: Politics will now supersede sound science and trash it Play Now | Play in Popup | Download

Madely Health Headlines Commentary for November 16, 2011

Light-activated compound kills cancer cells leaving normal cells unharmed when piggybacked with cancer-seeking antibodies Play Now | Play in Popup | Download

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Light-activated cancer drugs tested

Reference:

National Cancer Institute

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Madely Health Headlines Commentary for November 9, 2011

The Maplesoft Centre opens in Ottawa Play Now | Play in Popup | Download

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Ottawa Regional Cancer Foundation

Madely Health Headlines Commentary for November 3, 2011

Combination radiation and anti-androgen therapy for specific form of prostate cancer improves survival Play Now | Play in Popup | Download

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Combination Tx Is Better in Locally Advanced Prostate Cancer

Reference:

Combined androgen deprivation therapy and radiation therapy for locally advanced prostate cancer: a randomised, phase 3 trial

Madely Health Headlines Commentary for October 14, 2011

Vitamin E supplementation does not prevent prostate cancer:study Play Now | Play in Popup | Download

Source:

Vitamin E Is Linked to Prostate Cancer 

Reference:

Klein E, et al “Vitamin E and the risk of prostate cancer: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)” JAMA 2011; 306: 1549-1556.

Madely Health Headlines Commentary for October 7, 2011

US Preventive Task Force recommends against PSA testing for healthy men Play Now | Play in Popup | Download

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Panel advises against prostate cancer screening

Madely Health Headlines Commentary for October 6, 2011

Pancreatic cancer implicated in Steve Job's death Play Now | Play in Popup | Download

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Steve Jobs’ Pancreatic Cancer: A Timeline

Madely Health Headlines Commentary for September 29, 2011

Colonoscopy screening guidelines may change favouring testing in men at earlier age compared to women Play Now | Play in Popup | Download

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Men Should Be Tested for Colon Cancer at Younger Age Than Women

Reference:

Sex-Specific Prevalence of Adenomas, Advanced Adenomas, and Colorectal Cancer in Individuals Undergoing Screening Colonoscopy

Madely Health Headlines Commentary for September 9, 2011

Microchip implant monitors tumour growth Play Now | Play in Popup | Download

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Microchip implant monitors tumour growth

Madely Health Headlines Commentary for August 31, 2011

Targeted lung cancer therapy demonstrates how personalized medical therapy works Play Now | Play in Popup | Download

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New Lung Cancer Pill Highlights Improved Way of Treating Patients

Reference:

Butrynski JE, et al “Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor” N Engl J Med2010; 363: 1727-1733.