Skip to content

Archive

Category: Clinical Research

Madely Health Headlines Commentary for May 20, 2013

Source:

Now We Know Why Old Scizophrenia Medicine Works On Antibiotics-Resistant Bacteria

Reference:

Thioridazine Induces Major Changes in Global Gene Expression and Cell Wall Composition in Methicillin-Resistant Staphylococcus aureus

Madely Health Headlines Commentary for May 17, 2013

Source:

Scientists develop drug that may slow Alzheimer’s

Reference:

The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer’s disease mice

Madely Health Headlines Commentary for April 25, 2013

Source:

Clinical trial first for less invasive procedure to treat prostate cancer

Madely Health Headlines Commentary for April 15, 2013

Source:

New Technique Holds Promise For The Treatment Of Multiple Sclerosis And Cerebral Palsy

Reference:

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

Madely Health Headlines Commentary for April 8, 2013

Source:

Researchers probe link between autism and gastrointestinal problems

 

Madely Health Headlines Commentary for March 22, 2013

Source:

BP Control May Help Slow Alzheimer’s

Reference:

Rodrigue KM, et al “Risk factors for β-amyloid deposition in healthy aging: Vascular and genetic effects” JAMA Neurol 2013; DOI: 10.1001/jamaneurol.2013.1342.

Madely Health Headlines Commentary for March , 2013

Source:

Excellent Results For MS Drug “Plegridy”

Reference:

The results were presented at the American Academy of Neurology’s 65th Annual Meeting. It is not published.

Further it compares the drug to placebo, a useless marker for clinicians. We want to know how it fares against other medication of a similar class at least and how it compares to other medication in use today.  It also refers to relative and not absolute risk reduction.

Madely Health Headlines Commentary for March 15, 2013

 

Madely Health Headlines Commentary for March 13, 2013

Source:

Ottawa sexual behaviours clinic helps science understand re-offenders

 

Madely Health Headlines Commentary for March 12, 2013

Source:

Ottawa Hospital tackling eating disorders

 

Madely Health Headlines Commentary for March , 2013

Source:

Nanoparticles Loaded With Bee Venom Kill HIV

Reference:

Cytolytic nanoparticles attenuate HIV-1 infectivity

Madely Health Headlines Commentary for March 7, 2013

Source: Stomach Cancer Test: ‘Bad’ Breath Sensor Can Indicate Illness Reference: A nanomaterial-based breath test for distinguishing gastric cancer from benign gastric conditions

Madely Health Headlines Commentary for February , 2013

Source:

Large genetic study paves way for new treatment of mental illness

Reference:

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

Madely Health Headlines Commentary for February 25, 2013

Source:

Reprogramming Alpha Cells To Fight Diabetes

Reference:

“Epigenomic plasticity enables human pancreatic α to β cell reprogramming”

Madely Health Headlines Commentary for January 23, 2013

Source:

New way to kill lymphoma without chemotherapy: Golden nanoparticle starves cancer cell to death

Reference:

S. Yang, M. G. Damiano, H. Zhang, S. Tripathy, A. J. Luthi, J. S. Rink, A. V. Ugolkov, A. T. K. Singh, S. S. Dave, L. I. Gordon, C. S. Thaxton. Biomimetic, synthetic HDL nanostructures for lymphomaProceedings of the National Academy of Sciences, 2013; DOI:10.1073/pnas.1213657110

Madely Health Headlines Commentary for January 10, 2013

Source:

Scandal of the poison pen-pushers: How doctors and patients are kept in the dark about potentially dangerous everyday drugs

 

Madely Health Headlines Commentary for November 16, 2012

Source:

When You Eat Is Just As Crucial As What You Eat

Reference:

Obesity in mice with adipocyte-specific deletion of clock component Arntl

Madely Health Headlines Commentary for November 14, 2012

Source:

Doctors shocked as neuroscientist ‘talks’ with man in vegetative state

 

Madely Health Headlines Commentary for November 8, 2012

Source:

One test may ‘find many cancers’

Reference:

The DSB Biomarkers Pilot Study

Madely Health Headlines Commentary for October 16, 2012

Source:

Abbott Labs rises on hepatitis C drug data

Reference:

This press release does not cite published studies. Nor do we know if there were negative outcomes in other clinical trials. THere is no obligation on the part of pharma to release details of stiudies that cast a negative outcome for their product.

 

Madely Health Headlines Commentary for October 4, 2012

Source:

Researchers poised to test stem cells for treating damaged hearts

 

 

Madely Health Headlines Commentary for October 3, 2012

Source:

Breast cancer treatment targets tumours with few side effects

Reference:

Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

Madely Health Headlines Commentary for September 21, 2012

Source:

Largest cancer center in US launches major initiative to cure 8 forms of the disease

 

Madely Health Headlines Commentary for September 20, 2012

Source:

Experimental MS drug shown to reduce relapses: studies

Reference:

Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis

Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

Madely Health Headlines Commentary for August 2, 2012

Source:

Caffeine May Help Treat Parkinson’s Disease

Reference:

Caffeine for treatment of Parkinson disease

Madely Health Headlines Commentary for August 1, 2012

Source:

Science takes tiny steps toward a cure for AIDS

 

Madely Health Headlines Commentary for July 27, 2012

Source:

More Evidence That Shift Work Might Raise Heart Risks

Reference:

Daniel Hackam, M.D., Ph.D., clinical pharmacologist, Stroke Prevention & Atherosclerosis Research Centre, London, Ontario, Canada; Gregg Fonarow, M.D., professor, cardiovascular medicine, University of California, Los Angeles; July 26, 2012, BMJ, online

Madely Health Headlines Commentary for July 20, 2012

Source:

Prostate Cancer Surgery Fails to Cut Death Rate in Study

Reference:

Radical Prostatectomy versus Observation for Localized Prostate Cancer

Madely Health Headlines Commentary for July 6, 2012

Source:

Vitamin D in high doses may prevent fractures

Reference:

Heike A. Bischoff-Ferrari, Walter C. Willett, Endel J. Orav, Paul Lips, Pierre J. Meunier, Ronan A. Lyons, Leon Flicker, John Wark, Rebecca D. Jackson, Jane A. Cauley, Haakon E. Meyer, Michael Pfeifer, Kerrie M. Sanders, Hannes B. Stähelin, Robert Theiler, Bess Dawson-Hughes. A Pooled Analysis of Vitamin D Dose Requirements for Fracture PreventionNew England Journal of Medicine, 2012; 367 (1): 40 DOI: 10.1056/NEJMoa1109617

Madely Health Headlines Commentary for June 14, 2012

 

 

Source:

Cold virus holds promise as cancer therapy: study

Reference:

Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Madely Health Headlines Commentary for June 11, 2012

 

 

Source:

Fixing broken bones a growth industry

 

Madely Health Headlines Commentary for June 8, 2012

Source:

Alzheimer’s Vaccine Trial a Success

Reference:

Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer’s disease: randomised, double-blind, placebo-controlled, first-in-human study. The Lancet Neurology

Madely Health Headlines Commentary for June 1, 2012

Source:

Rat Paralysis Rehab Method Holds Clues for Aiding Humans

Reference:

Rehabilitation Restores Voluntary Motion in Paraplegic Rats

Madely Health Headlines Commentary for May 23, 2012

 

 

Source:

Google algorithm proves extremely useful in cancer study

Reference:

Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes

Madely Health Headlines Commentary for May 15, 2012

Source:

Fat hits your waistline fast, study says

Reference:

Physical Activity and Exercise in the Regulation of Human Adipose Tissue Physiology

Madely Health Headlines Commentary for May 8, 2012

 

 

Source:

Type 2 diabetes treatment may put disease in remission

 

Madely Health Headlines Commentary for May 7, 2012

 

 

Source:

U of O discovery offers hope for cancer, heart disease miracle drugs

Reference:

An oxygen-regulated switch in the protein synthesis machinery

Madely Health Headlines Commentary for May 3, 2012

 

 

Source:

Gene Therapy Safe in Decade-Long HIV Study That May Widen Use

Reference:

Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells

Madely Health Headlines Commentary for May 2, 2012

 

Madely Health Headlines Commentary for April 23, 2012

 

 

Source:

Medical Hypnosis: You Are Getting Very Healthy

 

Madely Health Headlines Commentary for March , 2012

 

 

Source:

Study results give patient care boost

 

Madely Health Headlines Commentary for October 4, 2011

Source:

Nobel winner used his own discovery in cancer fight

 

Madely Health Headlines Commentary for September 23, 2011

Source:

Stem cell trial for eye condition to go ahead

 

Madely Health Headlines Commentary for September 1, 2011

Source:

Canadian-made virus shows promise as cancer treatment

Reference:

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

Madely Health Headlines Commentary for August 30, 2011

Source:

New drug could cure nearly any viral infection

Reference:

Broad-Spectrum Antiviral Therapeutics

Madely Health Headlines Commentary for August 5, 2011

Source:

Scientists a step closer to Hepatitis C vaccine

Reference:

Virus-Like Particles Pseudotyped for HCV Trigger Broadly Neutralizing Antibodies

Madely Health Headlines Commentary for July 14, 2011

Source:

Sunburn Pain Discovery Could Benefit Inflammation Conditions

Reference:

CXCL5 Mediates UVB Irradiation-Induced Pain.”
John M. Dawes, Margarita Calvo1, James R. Perkins, Kathryn J. Paterson, Hannes Kiesewetter, Carl Hobbs, Timothy K. Y. Kaan, Christine Orengo, David L. H. Bennett, Stephen B. McMahon.
Sci Transl Med 6 July 2011: Vol. 3, Issue 90, p. 90ra60

Madely Health Headlines Commentary for July 11, 2011

Source:

Discovery of Natural Antibody Brings a Universal Flu Vaccine a Step Closer

Reference:

A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

Madely Health Headlines Commentary for July 8, 2011

Source:

Stem cell breakthrough raises hope of ending hunt for bone marrow

Reference:

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

Madely Health Headlines Commentary for July 5, 2011

Source:

Evidence “increasingly against” phone cancer risk

Reference:

Mobile phones ‘unlikely to cause brain tumours’

Mobile Phones, Brain Tumours and the Interphone Study: Where Are We Now?