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Category: Clinical Research

Madely Health Headlines Commentary for October 4, 2011

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Nobel winner used his own discovery in cancer fight

 

Madely Health Headlines Commentary for September 23, 2011

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Stem cell trial for eye condition to go ahead

 

Madely Health Headlines Commentary for September 1, 2011

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Canadian-made virus shows promise as cancer treatment

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Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

Madely Health Headlines Commentary for August 30, 2011

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New drug could cure nearly any viral infection

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Broad-Spectrum Antiviral Therapeutics

Madely Health Headlines Commentary for August 5, 2011

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Scientists a step closer to Hepatitis C vaccine

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Virus-Like Particles Pseudotyped for HCV Trigger Broadly Neutralizing Antibodies

Madely Health Headlines Commentary for July 14, 2011

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Sunburn Pain Discovery Could Benefit Inflammation Conditions

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CXCL5 Mediates UVB Irradiation-Induced Pain.”
John M. Dawes, Margarita Calvo1, James R. Perkins, Kathryn J. Paterson, Hannes Kiesewetter, Carl Hobbs, Timothy K. Y. Kaan, Christine Orengo, David L. H. Bennett, Stephen B. McMahon.
Sci Transl Med 6 July 2011: Vol. 3, Issue 90, p. 90ra60

Madely Health Headlines Commentary for July 11, 2011

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Discovery of Natural Antibody Brings a Universal Flu Vaccine a Step Closer

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A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses

Madely Health Headlines Commentary for July 8, 2011

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Stem cell breakthrough raises hope of ending hunt for bone marrow

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Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

Madely Health Headlines Commentary for July 5, 2011

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Evidence “increasingly against” phone cancer risk

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Mobile phones ‘unlikely to cause brain tumours’

Mobile Phones, Brain Tumours and the Interphone Study: Where Are We Now?

 

 

 

Madely Health Headlines Commentary for June 30, 2011

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Feds OK funding for MS ‘liberation therapy’ trials

 

Madely Health Headlines Commentary for June 20, 2011

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Experimental Vaccine Seems to Cure Prostate Cancer in Mice

 

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Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors

 

Madely Health Headlines Commentary for June 13, 2011

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Carleton researcher helps find link between nicotine, thinness

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Nicotine Decreases Food Intake Through Activation of POMC Neurons

Madely Health Headlines Commentary for May 23, 2011

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Viagra® Could Reduce Multiple Sclerosis Symptoms

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Pifarré et al. Sildenafil (Viagra) ameliorates clinical symptoms and neuropathology in a mouse model of multiple sclerosis, Acta Neuropathol (2011) 121:499–508.

Madely Health Headlines Commentary for May 20, 2011

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Electrostimulation helps paralyzed man stand up

Madely Health Headlines Commentary for April 26, 2011

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Too many deadly cancers go underfunded: report

Madely Health Headlines Commentary for April 18, 2011

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Do Immune System Ills Help Drive Type 2 Diabetes?

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Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

Madely Health Headlines Commentary for March 7, 2011

Source: Doctors discover 13 genes behind heart disease    

The true secret of youth? Exercise

Madely Health Headlines Commentary for January 4, 2011

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New blood test helps spot migrating cancer cells

A Blood Test for Cancer

Madely Health Headlines Commentary for November 19, 2010

Source: Zapping nerves helps control high blood pressure

Analysis: ‘Kidney zapping’ eases high blood pressure

Reference: Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial

Madely Health Headlines Commentary for November 8 , 2010

Source: Scientists Convert Skin Cells Into Blood Cells Directly Reference: Direct conversion of human fibroblasts to multilineage blood progenitors

Madely Health Headlines Commentary for November 3, 2010

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Researchers uncover new approach to fighting viruses

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Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

Madely Health Headlines Commentary for October 21, 2010

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Hope for kids with dangerous inflammatory disease

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Immunosuppressants Improves Neurological Outcomes in Children With Angiitis of the CNS

Madely Health Headlines Commentary for October 19, 2010

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Statin Drugs May Cut Risk of Colorectal Cancer

Madely Health Headlines Commentary for October 14 , 2010

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Ottawa researcher behind Parkinson’s discovery: Key markers may identify people who are at risk of developing the disease

Madely Health Headlines Commentary for September 6, 2010

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Cortisol Levels In Hair Linked To Heart Attack Risk

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Hair cortisol and the risk for acute myocardial infarction in adult men

Madely Health Headlines Commentary for August 25, 2010

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Genetic effects of vitamin D studied

Madely Health Headlines Commentary for August 20, 2010

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‘Magic drug’ gives hope to bipolar patients

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“mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists.”
Nanxin Li, Boyoung Lee, Rong-Jian Liu, Mounira Banasr, Jason M. Dwyer, Masaaki Iwata, Xiao-Yuan Li, George Aghajanian, Ronald S. Duman
Science, 20 August 2010: Vol. 329. no. 5994, pp. 959 – 964
DOI: 10.1126/science.1190287

Madely Health Headlines for July 2, 2010

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Live Long and Proper: Genetic Factors Associated with Increased Longevity Identified

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Genetic Signatures of Exceptional Longevity in Humans

Madely Health Headlines for June 29, 2010

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Cholesterol drugs for the healthy still debatable

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Cholesterol Lowering, Cardiovascular Diseases, and the Rosuvastatin-JUPITER Controversy

Madely Health Headlines for  June 11, 2010

Source: Study backs heart-healthy effect of dairy fat Resources: Dr. Yoni Freehoff provides an excellent analysis of the “study” and its many methodological flaws. Please see his June 10, 2010 post.

Madely Health Headlines for June 10, 2010

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Genetic finding paves way for controversial autism testing

Madely Health Headlines Commentary for May 28, 2010

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Immune System Troubles Could Spark Behavior Woes

Madely Health Headlines Commentary for May 13, 2010

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Cancer’s sweet tooth becomes a target

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Metabolic Modulation of Glioblastoma with Dichloroacetate

Madely Health Headlines Commentary for May 6, 2010

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MS patients rally to demand CCSVI treatment

Madely Health Headlines Commentary for April 30, 2010

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Could a hormone spray improve empathy in men?

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Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans

Madely Health Headlines Commentary for April 29, 2010

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Heat Helps Chemo Fight Soft-Tissue Sarcoma

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Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study

Madely Health Headlines Commentary for April 20, 2010

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Older Drug Cuts Breast-Cancer Risk More

Madely Health Headlines Commentary for April 13, 2010

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Monoclonal Antibodies Promise New Chances For Ovarian Cancer Therapy: Research Study

Madely Health Headlines Commentary for April 5, 2010

Source: Rare ‘supertaskers’ can balance driving and cellphone

Madely Health Headlines Commentary for March 18, 2010

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Could Lowering Blood Pressure Help Stop Dementia?

Madely Health Headlines Commentary for March 15, 2010

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Treatment fails to prevent heart attacks in diabetics

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Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus

Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus

NEJM Editorial: ACCORD and Risk-Factor Control in Type 2 Diabetes

Madely Health Headlines Commentary for March 12, 2010

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Birth-Control Pills Cut Cancer, Lengthen Women’s Lives in Study

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Mortality among contraceptive pill users: cohort evidence from Royal College of General Practitioners’ Oral Contraception Study

Madely Health Headlines Commentary for March 11, 2010

Source: B.C. team makes a breakthrough in lymphoma treatment Reference: Tumor-Associated Macrophages and Survival in Classic Hodgkin’s Lymphoma

Madely Health Headlines Commentary for March 10, 2010

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Tumor-Melting Virus vs. Prostate Cancer

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Oncolytic Viral Therapy for Prostate Cancer: Efficacy of Reovirus as a Biological Therapeutic

Madely Health Headlines Commentary for March 8, 2010

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Researchers take aim at digestive disorder

Madely Health Headlines Commentary for March 2, 2010

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Simple Index Predicts Risk of Death, Hospital Readmission

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Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the community

Madely Health Headlines Commentary for March 1, 2010

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Neuroimaging technique shows potential of bapineuzumab treatment and might be useful in assessing other drugs for Alzheimer’s Disease

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11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer’s disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

Madely Health Headlines Commentary for February 17, 2010

Source: Bilingual Babies: The Roots of Bilingualism in Newborns

Madely Health Headlines Commentary for February 9, 2010

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Centre to test for controversial condition linked to MS